In recent years, the scientific publishing world has been significantly changed from focusing on impact factor to encouraging scientific merit and from subscriptional access to open access (Wu, 2018). Journal of Molecular Cell Biology (JMCB), which was launched in October 2009, started a new journey following the new routes in the scientific publishing world from the beginning of 2019. Here, I would like to go through what JMCB has fulfilled in the first year of change.